Harkness San Luis is located in a very centric neighbourhood of the beautiful colonial city of San Luis Potosi, a city with a metro área population of just over 1 million. San Luis Potosi is the second fastest growing economy in the country and host to many new national and international corporations such as BMW.

San Luis Potosi is home to the Universidad Autonoma de San Luis Potosi, the state´s largest university and the first autonomous university in Mexico.
The city is home to many museums among them the National Mask Museum, Museo Laberinto de las Ciencias, Museo Leonora Carrington, and Museo Federico Silva.